We are working on cellular biology issues (single cell and multicellular mechanics, adhesion, motility and tumor escape) with biophysical approaches on models such as embryonic multicellular spheroids, breast and prostate cancer cells, Dictyostelium Discoideum. They also works on membrane physics in the context of biolubrication and sonoporation using supported phospholipids bilayers.

We are involved in both fundamental projects (cell-cell adhesion, collective cell migration, rheological properties of tissues, cell-cell interactions) and applied projects (role of lipid membranes in biolubrication, sonoporation, phenotypic sorting of cancer cells, development of lab-on-a-chips using confined tumor spheroids or cancer cells for drug screening …).

 

Physics of Cancer

Tissue Mechanics

How do assemblies of cells deform, exchange neighbors under stress?

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Cell Motility

Physics of Membranes

Methods Developments

Tools developped to quantify biological processes

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Contact : Jean Paul RIEU  - Institut Lumière et Matière - Université Claude Bernard Lyon 1 et CNRS - Bâtiment Brillouin, 43 Boulevard du 11 Novembre - 69622 Villeurbanne Cedex. France - jean-paul.rieu at univ-lyon1.fr - Phone: +33-(0)4 72 43 11 42 - Fax: +33-(0)4 72 43 26 48

 

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