Séminaire

Jeudi 23 Octobre 2025 à 11h00.

Molecular programming of materials using DNA.

Rémi Mérindol
(Laboratoire Charles Coulomb)

Salle de séminaires Lippmann

Invité(e) par
Nicolas Bain

présentera en 1 heure :

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Résumé / Abstract :
The defined sequences of biomolecules (peptides, DNA, glycans…) drive their self-assembly into a mesmerizing diversity of functional materials. Our difficulties to produce sequence controlled macromolecules, limits our capacities to reproduce the performances of biological materials. Decades of progress in molecular biology overcame some of the challenges associated with the synthesis of sequence-controlled DNA strands. In this seminar I will give a quick overview of the strategies available to build upon this progress and to program the behaviour of synthetic materials using DNA. I will illustrate the potential of DNA for material programming with two of our recent work. First, I will show how to use DNA to design dynamic hydrogels inspired by vitrimers that reorganize via an associative exchange mechanism. Then, I will present the design of mechanofluorescent hydrogels. In both examples I will show to link (supra)molecular control and macroscale material properties.
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