Séminaire

Vendredi 26 Mars 2021 à 11h00.

Mechanics of cells and tissues

''Cell migration and cell mechanics play a crucial role in a number of key biological processes, such as embryo development or cancer metastasis. In this context, it is important to understand the way cells control their own material properties and mechanically interact with their environment. In this talk, I will report experimental studies on the mechanical response of in-vitro epithelial monolayers. The material exhibits a strong time-dependant response over a broad distribution of time-scales. The combination of mechanical characterisation with biological perturbations offers new insight into the mechanisms exploited by cells and tissue to control their mechanical properties. The polarity of the tissue also induces differential contractility between the apical and basal side of the monolayer leading to spontaneous curvature and the curling of the monolayer along free-edges.''